Templating a polymer-scaffolded dynamic combinatorial library
نویسندگان
چکیده
منابع مشابه
Templating a polymer-scaffolded dynamic combinatorial libraryw
Dynamic combinatorial chemistry (DCC) has emerged in recent years as a powerful tool for the discovery of molecular receptors. DCC uses reversible covalent reactions to link together building blocks, forming libraries of compounds whose product distributions are under thermodynamic control. The reversible nature of the linkages enables the library members to reconfigure their structures by exch...
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A conceptually new approach to the design of macromolecular receptors for lectins is outlined. Carbohydrate-functionalised Polymer-Scaffolded Dynamic Combinatorial Libraries (PS-DCLs) have been prepared in aqueous solution by the reversible conjugation of carbohydrates possessing acylhydrazide functionalities in their aglycone on to an aldehyde-functionalised polymer scaffold. PS-DCLs have been...
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ژورنال
عنوان ژورنال: Chemical Communications
سال: 2011
ISSN: 1359-7345,1364-548X
DOI: 10.1039/c1cc11998b